Browse Articles

A model for angle evolution in conical piles formed using the fixed funnel method

Capaldi et al. | Jul 20, 2026

A model for angle evolution in conical piles formed using the fixed funnel method

When granular materials are poured onto a surface, they form conical piles whose slopes increase before reaching a stable angle of repose. We found that this angle evolution follows a previously unrecognized two-phase exponential growth pattern that is conserved across granular materials with diverse particle properties. The parameters of this model correlate with particle friction and are influenced by deposition conditions, providing a quantitative framework for describing pile formation.

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Simulating single versus cocktail antibiotic effects on the human gut microbiome

Patel et al. | Jul 19, 2026

Simulating single versus cocktail antibiotic effects on the human gut microbiome
Image credit: Volodymyr Hryshchenko

This study, uses SimulATe to model changes in microbial diversity and community structure upon administering a cocktail of antibiotics versus a single antibiotic. The authors hypothesized that antibiotic cocktails, particularly those combining broad-spectrum drugs like tetracyclines and trimethoprims, would cause a more significant reduction in gut microbial diversity compared to single-drug treatments. The findings confirmed a greater loss of microbial diversity with combinatorial treatments compared to single-drug treatments. While individual antibiotics dynamically reshaped the surviving species of the microbiome, antibiotic cocktails frequently cleared all species of the gut microbiome.

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The effects of a high-sucrose diet on the survival of Drosophila melanogaster from a bacterial infection

Warwick et al. | May 22, 2026

The effects of a high-sucrose diet on the survival of <i>Drosophila melanogaster</i> from a bacterial infection

Excess sucrose consumption has been associated with several health problems, including inflammation and potential negative effects on immune function. However, the exact relationship between sucrose intake and immunity remains unclear, especially during bacterial infections. This study examined how sucrose intake affected the survival of fruit flies following oral infection with the bacterial pathogen Serratia marcescens.

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Evaluating the performance of Q-learning-based AI in auctions

Liu et al. | Nov 09, 2025

Evaluating the performance of Q-learning-based AI in auctions
Image credit: Liu and Liu

Advertising platforms like Google Ads use AI to drive the algorithms used to maximize advertisers benefits. This study shows that AI does not adjust it strategy based on auction type and highlights the limitations of AI running without explicit guidance.

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Quantifying natural recovery of dopamine deficits induced by chronic stress

Josyula et al. | Oct 27, 2025

Quantifying natural recovery of dopamine deficits induced by chronic stress
Image credit: Shawn Day

Here the authors investigated the natural recovery of stress-induced dopamine-related gene deficits in C. elegans by measuring the expression of cat-2 (dopamine biosynthesis) and sod-2 (oxidative stress) following exposure to starvation or hydrocortisone. They found that the reversibility of sod-2 and the expression of cat-2 were highly dependent on the type and severity of the stressor, suggesting that the body's natural ability to recover from dopamine dysfunction has biological limitations.

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Reinforcement learning in 2-D space with varying gravitational fields

Rousseau et al. | Jun 07, 2025

Reinforcement learning in 2-D space with varying gravitational fields
Image credit: NASA

In this study the authors looked at the ability to navigate planes in space between randomly placed planets. They used machine and reinforcement learning to run simulations and found that they were able to identify optimal paths for travel. In the future these techniques may allow for safer travel in unknown spaces.

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Testing filtration capabilities of household fabrics for protection against airborne contaminants

Shah et al. | May 31, 2025

Testing filtration capabilities of household fabrics for protection against airborne contaminants

Toxic particulates in the atmosphere pose significant health risks, and while modern masks can help reduce inhalation of these pollutants, their availability may be limited during health crises. This study evaluated the effectiveness of household fabrics (cotton, fleece, wool, and rayon) as particulate filters, finding that cotton outperformed the others in filtration efficiency, while rayon was the least effective. The findings suggest that cotton is a preferable alternative for filtration purposes, while rayon should be avoided.

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