The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.
Read More...Novel anticancer effects of melatonin and berberine via signaling pathways in colorectal cancer and lymphoma
The authors looked at the ability of berberine in combination with melatonin to have anticancer effects when tested in an in vitro cell model.
Read More...AeroPurify: Autonomous air filtration UAV using real-time 3-D Monte Carlo gradient search
Here the authors present an autonomous drone air filtration system that uses a novel algorithm, the gradient ascent ML particle filter (GA/MLPF), to efficiently locate and mitigate outdoor air pollution. They demonstrate that their GA/MLPF algorithm is significantly more efficient than the conventional gradient ascent algorithm, reducing both the time and number of waypoints needed to find the source of pollution.
Read More...Investigating the anticancer effects of Uvularia perfoliata
This paper investigates the potential anticancer properties of Uvularia perfoliata by testing its effects on the viability of uveal melanoma cells.
Read More...Cardiovascular Disease Prediction Using Supervised Ensemble Machine Learning and Shapley Values
The authors test the effectiveness of machine learning to predict onset of cardiovascular disease.
Read More...A novel approach for predicting Alzheimer’s disease using machine learning on DNA methylation in blood
Here, recognizing the difficulty associated with tracking the progression of dementia, the authors used machine learning models to predict between the presence of cognitive normalcy, mild cognitive impairment, and Alzheimer's Disease, based on blood DNA methylation levels, sex, and age. With four machine learning models and two dataset dimensionality reduction methods they achieved an accuracy of 53.33%.
Read More...The extent to which storefront alcohol advertising differs by community profile in Michigan
Here, recognizing that alcohol manufacturers may target ethnic minorities and youths with specific forms of advertisements based on previous studies, the authors considered how alcohol storefronts differ depending on the community they are located in. Specifically, they looked at differences between Metro-Dtroit suburban communities of high- and low-incomes. They found that alcohol stores in the low-income areas had more and larger alcohol and malt liquor advertisements per store along with being within 1,000 feet of a school.
Read More...Virtual Screening of Cutibacterium acnes Antibacterial Agent Using Natural Compounds Database
A common form of Acne is caused by a species of bacterium called Cutibacterium acnes. By using a predictive algorithm and structural analysis, the authors identified 5 small molecules with high affinity to growth factors in Catibacterium acnes. This has potential implications for supplemental skincare products.
Read More...Discovery of the Heart in Mathematics: Modeling the Chaotic Behaviors of Quantized Periods in the Mandelbrot Set
This study aimed to predict and explain chaotic behavior in the Mandelbrot Set, one of the world’s most popular models of fractals and exhibitors of Chaos Theory. The authors hypothesized that repeatedly iterating the Mandelbrot Set’s characteristic function would give rise to a more intricate layout of the fractal and elliptical models that predict and highlight “hotspots” of chaos through their overlaps. The positive and negative results from this study may provide a new perspective on fractals and their chaotic nature, helping to solve problems involving chaotic phenomena.
Read More...Comparing the Effect of Stent Geometry on Blood Flow Rate of Curved Coronary Artery Stenosis
Coronary heart disease (CHD) is a global disease that causes fatal buildup of plaque in the arteries. Currently stents are placed in the artery for many patients with CHD to support proper blood flow. Here, the authors build a system to explore how the shape of the stent affects blood flow rate, a finding that can help optimize stents for patients.
Read More...Pancreatic Adenocarcinoma: An Analysis of Drug Therapy Options through Interaction Maps and Graph Theory
Cancer is often caused by improper function of a few proteins, and sometimes it takes only a few proteins to malfunction to cause drastic changes in cells. Here the authors look at the genes that were mutated in patients with a type of pancreatic cancer to identify proteins that are important in causing cancer. They also determined which proteins currently lack effective treatment, and suggest that certain proteins (named KRAS, CDKN2A, and RBBP8) are the most important candidates for developing drugs to treat pancreatic cancer.
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