Using county-level epidemiological data from the Texas Department of State Health Services, this study implemented an SIRV model in Python to simulate measles transmission in Gaines County under different vaccination scenarios.
Read More...Increasing MMR vaccination rates substantially reduces measles infections in Gaines County, Texas
Using county-level epidemiological data from the Texas Department of State Health Services, this study implemented an SIRV model in Python to simulate measles transmission in Gaines County under different vaccination scenarios.
Read More...Leaky expression of PRMT1 in Escherichia coli and redox regulation of its histone methyltransferase activity
This study characterizes recombinant human Protein arginine methyltransferase 1 (PRMT1) expressed in Escherichia. coli and reveals that the enzyme exhibits leaky expression even without isopropyl β-D-1-thiogalactopyranoside (IPTG) induction. Through in vitro histone methyltransferase assays, we demonstrate that PRMT1 activity toward histone H4R3 is enhanced by dithiothreitol (DTT) in a dose-dependent manner but remains unresponsive to β-mercaptoethanol. These findings highlight the critical role of redox conditions in regulating PRMT1 catalytic function and provide a practical framework for future biochemical and kinetic studies.
Triboelectric nanogenerators and self-powered sensors for smart farming
The authors designed a triboelectric nanogenerator with the goal to use it as an energy source for smart farming.
Read More...In silico design of an epitope-based vaccine for Rocio virus using phage display and E. coli expression system
The explored the potential of an epitope-based vaccine for Rocio virus using computational methods and M13 bacteriophage technology. Researchers identified 30 promising B- and T-cell epitopes and designed vaccine candidates using both phage display and E. coli expression systems.
Read More...A 3D printed triboelectric nanogenerator for bridge vibration energy harvesting and sensing
This study strongly illustrates that optimizing 3D printing parameters would enhance a triboelectric nanogenerator's performance. The design improvements substantiate the potential of optimized, 3D-printed TENGs for developing scalable, cost-effective solutions for powering low-energy electronics, particularly in applications such as structural health monitoring.
Read More...Functionalized graphene oxide nanoparticles for improved saltwater treatment
The authors investigated the efficacy of functionalized graphene oxide nanoparticles for turning saltwater to freshwater.
Read More...OTGP: An innovative biometric authentication system with on-the-go passwords using a novel typing signature
This manuscript describes a new method of on-the-go passwords using typing characteristics. The authors developed a keyboard and keystroke recording setup and tested it with 30 participants. The results indicated the five chosen parameters are distinct across participants yet consistent across time for each participant, making it a plausible candidate for a behavior-based password system.
Read More...De novo design of a dual-target inhibitor against tau phosphorylation and acetylation for Alzheimer's therapy
The authors use computational methods to compare tau acetylation to the better studied tau phosphorylation in Alzheimer's disease and then design and computationally test a new drug to prevent abnormal post-translational modifications of tau.
Read More...Bacteriophage TLS sensitizes Escherichia coli to antibiotics
Antibiotic resistance is a growing global health threat, and one strategy to combat it is using bacteriophages to enhance the effectiveness of existing antibiotics. This study tested whether targeting the TolC protein in E. coli with the TLS bacteriophage would increase bacterial sensitivity to antibiotics.
Read More...SeniorConnect: A low-cost, app-based real-time alert system to connect seniors with their caregivers
The authors design and test an easy-to-use and cost-effective mobile app-based alert system to help senior citizens rapidly communicate with caregivers in emergencies or when in need of assistance.
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