Browse Articles

This study examines how environmental conditions influence the abundance and ecological role of the sea cucumber Opheodesoma spectabilis in Kāneʻohe Bay. Field observations and laboratory experiments showed that the species is more common in algae-dominated sandy habitats, where it improves water clarity and increases dissolved oxygen through bioturbation. However, exposure to very high temperatures caused rapid mortality, suggesting that marine heat waves could threaten this species and the ecological functions it provides.

This paper discusses how the conditions at the center of stars affects the nuclear reactions that happen inside these stars. We focused on the effect of temperature and density and found that these two properties interacted to create a greater effect when combined than when separate.

Here the authors investigated a combination therapy to target the Kirsten rat sarcoma viral oncogene homolog mutation in lung cancer, by analyzing publicly available data. Their findings indicate that the combination therapy of CA170 and Kvax enhances helper T cell function and improves cytotoxic T lymphocyte infiltration, while Kvax alone drives plasma and memory B cell proliferation.

The authors looked at how pharmacokinetics changed depending on the use of an in vitro or an in vivo model.

Determination of Penalty Kick Success in Soccer

The authors looked at four members of the tetracycline antibiotic family/class against four different species of bacteria.

This study examined the impact of erosion on the performance of a triangular aerofoil at a low Reynolds number (Re = 10,000), relevant for harsh conditions like those on Mars.

Systematic consumption of traditional foods is a popular way of treating diseases in India. Rasam, a soup of spices and tomato with a tamarind base, is a home remedy for viral infections such as the common cold. Here, we investigate if rasam, prepared under household conditions, exhibits antibacterial activity against Escherichia coli and Staphylococcus aureus, two common pathogenic bacteria. Our results show rasam prepared under household conditions lacks antibacterial activity despite its ingredients possessing such properties.

The global mental health crisis has led to increased substance abuse among youth. Prescription drug abuse causes approximately 115 American deaths daily. Understanding intergenerational transmission of substance abuse is complex due to lengthy human studies and socioeconomic variables. Recent FDA guidelines mandate abuse liability testing for neuro-active drugs but overlook intergenerational transfer. Brown planaria, due to their nervous system development similarities with mammals, offer a novel model.

In this study, the authors looked at a proto-oncogene, KRAS, and searched for molecules that are predicted to be able to bind to the inactive form of KRAS. They found that a modified version of Irbesartan, a derivative of benzimidazole, showed the best binding to inactive KRAS.