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The authors use machine learning to develop an evidence-based detection tool for identifying human trafficking.

Given an association between nicotine addiction and gene expression, we hypothesized that expression of genes commonly associated with smoking status would have variable expression between smokers and non-smokers. To test whether gene expression varies between smokers and non-smokers, we analyzed two publicly-available datasets that profiled RNA gene expression from brain (nucleus accumbens) and lung tissue taken from patients identified as smokers or non-smokers. We discovered statistically significant differences in expression of dozens of genes between smokers and non-smokers. To test whether gene expression can be used to predict whether a patient is a smoker or non-smoker, we used gene expression as the training data for a logistic regression or random forest classification model. The random forest classifier trained on lung tissue data showed the most robust results, with area under curve (AUC) values consistently between 0.82 and 0.93. Both models trained on nucleus accumbens data had poorer performance, with AUC values consistently between 0.65 and 0.7 when using random forest. These results suggest gene expression can be used to predict smoking status using traditional machine learning models. Additionally, based on our random forest model, we proposed KCNJ3 and TXLNGY as two candidate markers of smoking status. These findings, coupled with other genes identified in this study, present promising avenues for advancing applications related to the genetic foundation of smoking-related characteristics.

Semantic segmentation - labelling each pixel in an image to a specific class- models require large amounts of manually labeled and collected data to train.

In this experiment, the authors modify the heat equation to account for imperfect insulation during heat transfer and compare it to experimental data to determine which is more accurate.

Machine learning systems are often expected to make fair decisions, yet the most widely used fairness criteria—independence, separation, and sufficiency—cannot generally be satisfied at the same time. In this study, students tested these criteria using a logistic regression model on a real-world student performance dataset and found that each criterion was met only at different prediction thresholds, with no threshold satisfying all three simultaneously. These results illustrate the inherent trade-offs in algorithmic fairness and highlight why achieving perfectly fair machine learning models is often impossible in practice.

This study investigates skin tone bias in artificial intelligence models used for dermatological disease classification and evaluates a CycleGAN-based data augmentation approach to improve diagnostic performance on darker skin types. We generated synthetic dark-skinned images to enhance dataset diversity and compared model performance before and after augmentation. The results demonstrate that augmentation with synthetic dermatological images can help reduce disparities in diagnostic performance across skin tones, highlighting a practical strategy for improving fairness in dermatology AI systems.

Algorithmic trading has been increasingly used by Americans. In this work, we tested whether including the opening, closing, and highest prices in three supervised learning models affected their performance. Indeed, we found that including all three prices decreased the error of the prediction significantly.

Here the authors sought to use three machine learning models to predict poverty levels in Cambodia based on available household data. They found teat multilayer perceptron outperformed the other models, with an accuracy of 87 %. They suggest that data-driven approaches such as these could be used more effectively target and alleviate poverty.

Quorum sensing (QS) is the process in which bacteria recognize and respond to the surrounding cell density, and it can be inhibited by certain antimicrobial substances. This study showed that illumination intensity data is insufficient for evaluating QS activity without proper statistical modeling. It concluded that modeling illumination intensity through time provides a more accurate evaluation of QS activity than conventional cross-sectional analysis.

This study combines gene expression, mutation profiling, and survival analysis of 17 clinically important genes in breast cancer, utilizing the TCGA-BRCA dataset. Our results show that there are different patterns of oncogene upregulation, different levels of tumor suppressor activity, and complicated survival associations. TP53 was the most frequently mutated gene in this cohort. The results underscore the significance of multidimensional genomic analyses for a comprehensive understanding of breast cancer biology and its therapeutic ramifications.