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Exogenous foliar thiamine application as an alternative strategy to mitigate lead stress in Lepidium sativum

Chen et al. | Oct 28, 2026

Exogenous foliar thiamine application as an alternative strategy to mitigate lead stress in <i>Lepidium sativum</i>

This study investigated whether thiamine (vitamin B1) could mitigate the harmful effects of lead contamination on plant growth. Using garden cress (Lepidium sativum), we found that lead exposure reduced plant growth and biomass, while thiamine treatment partially alleviated these effects, improving shoot length and overall plant length. These findings highlight the potential of thiamine as a simple strategy to improve plant resilience to heavy metal stress, with implications for agricultural productivity and food security.

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Simulating single versus cocktail antibiotic effects on the human gut microbiome

Patel et al. | Jul 19, 2026

Simulating single versus cocktail antibiotic effects on the human gut microbiome
Image credit: Volodymyr Hryshchenko

This study, uses SimulATe to model changes in microbial diversity and community structure upon administering a cocktail of antibiotics versus a single antibiotic. The authors hypothesized that antibiotic cocktails, particularly those combining broad-spectrum drugs like tetracyclines and trimethoprims, would cause a more significant reduction in gut microbial diversity compared to single-drug treatments. The findings confirmed a greater loss of microbial diversity with combinatorial treatments compared to single-drug treatments. While individual antibiotics dynamically reshaped the surviving species of the microbiome, antibiotic cocktails frequently cleared all species of the gut microbiome.

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